MedDesk
Tools

Creatinine clearance: Cockcroft-Gault

Renal

The 1976 estimate of creatinine clearance, still the basis of most drug-dosing tables (DOACs, many chemotherapy agents).

What you enter

  • Serum creatinine (mg/dL or µmol/L)
  • Age (years)
  • Weight (kg or lb)
  • Sex: Female / Male
FORMULACrCl = (140 − age) × weight(kg) × [0.85 if female] ÷ (72 × Scr mg/dL)
SourceCockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976;16:31-41ReviewedFormula and thresholds checked against the source on 2026-08-22. If the source updates, this line will say so.