MedDesk
Tools

FIB-4: liver fibrosis risk

Hepatology & GI

First-line non-invasive fibrosis test in MASLD. Below 1.3 rules out advanced fibrosis; above 2.67 goes to elastography or the hepatologist.

What you enter

  • Age (years)
  • AST (U/L)
  • ALT (U/L)
  • Platelets (×10⁹/L)
FORMULAFIB-4 = (age × AST) ÷ (platelets × √ALT)
SourceSterling RK et al. Hepatology 2006;43:1317-25; cut-offs per AASLD 2023 practice guidance on NAFLD/MASLDReviewedFormula and thresholds checked against the source on 2026-08-22. If the source updates, this line will say so.